What are Antiandrogens?
Anti androgens are also known as androgen antagonists. These are the class of drugs that prevent androgens from mediating their biological effect in the body. It blocks the androgens by inhibiting the production of androgen. There are three types of sex hormone antagonists and antiandrogens are one of its types. Anti androgens are used in the treatment of both males and females.
Anti-Androgen: Uses for Male
1. Prostate cancer
Prostate cancer is a condition in which the cells in the prostate gland starts to grow uncontrollably. The prostate is below the bladder and the size of the prostate changes with age. Androgens like testosterone are highly involved in the development and progression of prostate cancer. They naturally occur in the prostate gland and stimulates the cell division and tissue growth. Anti androgens are also effective in reducing the risk of developing prostate cancer.
2. Scalp Hair Loss
Scalp hair loss is also known as pattern hair loss or baldness. This condition is generally caused by the androgens and antiandrogens are considered as an effective drug for the hair loss. It blocks the testosterone from reaching the hair follicles and helps in the treatment of scalp hair loss.
3. Sexual deviance
It is a condition in which person constantly has sex on their mind and thinks about different ways to either encounter a sexual act with someone. Androgens increases sex drives and anti androgens help in reducing the sex drive in men. Anti androgens are used in the treatment of conditions of sex deviance such as hypersexuality, paraphilias, pedophilia etc..
Anti-Androgen: Uses for Female
1. High Androgen level
The condition in which the androgen level is excessively high in women is known as hyperandrogenism. It is commonly seen in women who suffer from PCOS. Some of the symptoms that arise due to high androgen levels are male pattern facial and body hair growth, voice deepening, broadening of the shoulders etc.. Anti androgens prevent and reverse the effects of androgens.
2. Skin and hair conditions
Anti androgens are also used in the treatment of skin and hair conditions such as its use in the treatment of acne, hirsutism, seborrhea, pattern hair loss etc.. Cyproterone acetate and spironolactone are the effective and the most commonly use anti androgens to treat the skin and hair conditions in women.
Different varieties of anti androgens
- Androgen Receptor antagonists
- Androgen synthesis inhibitors
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