Avastin 400 mg/16 ml Injection

What is Avastin 400 mg/16 ml Injection

Avastin Injection is a man-made antibody that is used in the treatment of certain Cancers.

It treats a specific type of Brain Tumor and Cancer of the kidney, colon, lung, liver, rectum, fallopian tube, ovary, and cervix.

The active component in Avastin 400 mg is Bevacizumab.

The manufacturer of this injection is Roche Products.

Uses of Avastin Injection

A 400 mg Bevacizumab Injection stops Cancer cells’ growth. It treats,

• Glioblastoma (a type of Brain Tumor)
• Certain types of Cancer of the lung, kidney, colon, liver, rectum, fallopian tube, ovary, and cervix
• Cancer of the membrane that lines the abdominal organs

How Avastin 400 mg works

As mentioned, Avastin contains Bevacizumab.

Bevacizumab belongs to the group of Angiogenesis inhibitors.

These inhibitors inhibit the Vascular Endothelial Growth Factor (VEGF).

The inhibition of VEGF results in the reduction of tumor blood vessels’ microvascular growth.

This reduction in the growth of tumor blood vessels limits the blood and oxygen supply to the tumor, restricting and stopping its growth.

Dosage

Avastin Injection will be administered to you by a qualified medical professional.

How to take Avastin Injection

It is an Intravenous injection, which means it will be slowly infused into a vein.

Typically, the first dosage is administered over 90 minutes. Suppose you will tolerate the initial dosage well. In that case, further infusions may be given over a shorter period of time (30 minutes).

Typically, Bevacizumab Injection is administered once every 2 to 3 weeks.

Overdose

The injection is administered slowly into the vein by a healthcare provider; therefore, there are fewer chances of overdose.

However, tell your doctor immediately if you experience chills, headaches, difficulty breathing, flushing, chest pain, or dizziness.

Strengths of Avastin Injection

Avastin Injection is available in one more strength:

• Avastin 100 mg/4 ml Injection

Avastin Injection side effects

There are some common to rare Avastin Injection side effects a person might go through after using this Bevacizumab Injection, such as:

• Rectal bleeding
• Nosebleed
• Headache
• Dry mouth and cough
• Increased blood pressure
• Back pain
• Missed menstrual cycle
• Diarrhea
• Nausea
• Loss of appetite
• Chest pain
• Kidney problems
• Pain or swelling in both legs

Interactions

Avastin Injection can interact with other drugs, conditions, and food.

Therefore, it is advisable to declare your medical history and the medications you are consuming to your doctor.

Drug interactions

Inform your physician if you take or have taken Sunitinib medication, as it can interact with Avastin.

Sunitinib also treats some types of Cancer.

Disease interactions

You should avoid Bevacizumab Injection if you have:

• Fistula
• Proteinuria
• GI Perforation
• Bleeding
• Hypertension
• PRES
• Thromboembolic disorders

Precautions

It would be best if you keep the following in mind before starting your treatment with this injection:

• Inform your physician if you are allergic to Bevacizumab
• If you went through surgery in the last four weeks or planning to have one in the next four weeks, declare it to your doctor to avoid any adverse effects
• You might have bleeding after using Avastin Injection. Seek medical attention if your bleeding does not stop
• If you have a slow-healing surgical incision or skin wound, inform your healthcare professional
• Avoid engaging in activities that may raise your risk of injury or bleeding. Use additional caution when brushing your teeth or shaving to prevent bleeding
• Do not breastfeed while using this injection for at least six months following the last dosage

Storage

Keep the Avastin 400 mg Injection in the refrigerator but do not freeze it.