Why Blood Type May Matter for COVID Infection?

One recent study revealed that people with certain blood types might be more susceptible to contract COVID-19 virus than others. Particularly, it was found that the novel coronavirus (SARS CoV-2) is specifically enticed to the blood group A antigen found on respiratory cells. The researchers emphasized a protein on the surface of the novel coronavirus called the receptor-binding domain (RBD), which is a part of the virus that gets attached to the host cells. And this makes it a significant target for scientists to discover how the virus infects people. 


In this lab study, the team evaluated how the RBD of the SARS CoV-2 virus interacted with the respiratory and red blood cells in A, B, and O blood types. 


The outcomes showed that the RBD of the SARS CoV-2 virus had a strong preference to identify and attach to the blood type A antigen found in the lungs of individuals with blood type A might provide a sense of the possible link between blood group A and COVID-19 infection.


It is fascinating that the viral RBD only actually prefers the type of blood group A antigens found on respiratory cells, which are supposedly how the virus enters most patients and infects them. 


This is a challenge because blood type is something that is inherited and not something that we can change. But if we can have a better comprehension of how the virus interacts with blood groups in people, we might be able to discover new medications or ways of prevention.


However, researchers believe that these outcomes alone cannot completely explain or predict how SARS CoV-2 affects patients of different blood types.


Blood Types and Diseases: What’s The Link?

Research has found that several diseases link to blood types. For example, blood type A is associated with stroke and cognitive impairment risk, although we don’t have much evidence for the same. Blood type O is known to protect against blood clots in the veins (called venous thrombosis) and heart attacks. 



Individuals with blood type A are known to be slightly at higher risk for COVID-19, but this doesn’t mean that people with other blood groups are protected or immune. They still need to practice COVID-19 protocols sincerely, such as frequent hand washing, keeping a safe distance of 2 meters from others, avoiding crowded places, etc.