Sildenafil is a drug that is sold under the name of viagra. Viagra is marketed in a pill form and is one of the most prescribed drugs for the treatment of men with erectile dysfunction, with pulmonary hypertension, and raynaud’s phenomenon.
The prevalence of sexual dysfunctioning is rising rapidly throughout the world and erectile dysfunction is one of the conditions that is affecting a large number of men and it is a condition that severely impacts the quality of life of an individual. The process of erectile function is not simple, but it involves the normal functioning of various other systems of the body.
Erectile dysfunction is defined as a condition in which maintaining and attaining satisfied erections is a questionable aspect for a man. In this condition, man fails to achieve erections that are sufficient enough to have a satisfying sexual intercourse. There are many factors that play a role in the functioning of erectile system and impairment in any factor can lead to the development of erectile dysfunction. Hormonal, neurological, psychological and vascular factors play an important role in attaining penile erection during sexual activity. It is a complex process which involves psychosocial, neural and vascular component.
Erectile dysfunction can be caused by certain neurological disorders such as Parkinson’s disease, Alzheimer’s disease, multiple sclerosis, and spinal cord injury. Sometimes, certain penile abnormalities can also affect erections and these conditions include foreskin problems, penile curvature, benign and malignant genital dermatoses, and fibrosis within the corpus cavernosum.
Sildenafil is an oral phosphodiesterase type 5 inhibitor which is considered to be one of the best therapy for erectile dysfunction and it is due to its effectiveness and low rate side effects. Not only erectile dysfunction, sildenafil is also a recommended dose to treat other sexual problems. Sildenafil is a hypertensive drug. Multiple studies have reported that a significant improvement is witnessed in patients having erectile dysfunction after consumption of sildenafil as compared to those patients who did not take sildenafil.
Getting an erection is a complicated process which requires an increased flow of blood in the penis region which results from the messages that are sent to the blood vessels in the penis. Sildenafil works by blocking or inhibiting the phosphodiesterase enzyme which leads to the degradation of cGMP (Cyclic guanosine monophosphate). Availability of cGMP is important to get or maintain the proper erection as it relaxes the muscles in the penis region and allows the blood flow to the penis region, which results in an erection. It is important to note that sildenafil works only after sexual stimulation. This is because When the brain senses sexual stimulation, it sends an impulse to the nerves of the penis that causes the muscles of the corpora muscles to relax.
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There are conditions under which one should not take sildenafil . Some such conditions include
- If you are taking nitrates
- If you are taking poppers such as amyl nitrite.
- If you are allergic to any ingredient that is present in sildenafil.
- If you have heart problems
- If you are taking any other phosphodiesterase type 5 inhibitor such as cialis
- If you are taking medicines that are used to treat high blood pressure
- If you are taking medicines called HIV protease inhibitors
- Some types of antibiotics can also interact with viagra
Sometimes consumption of sildenafil can cause some side effects and the most common side effects of sildenafil are indigestion, headache, back pain, flushing, stuffy nose, and muscle pain. Generally, these side effects are mild but it is essential to know that if you experience any serious side effect then contact the doctor as soon as possible. Taking an overdose of viagra can cause serious side effect such as an erection that lasts for more than four hours. So do not take more than one dose in a day.
It should be noted that consumption of viagra should be done only after consulting the doctor as there are certain medicines that are known to interfere with this drug and the consumption of this drug should be avoided with such medicines. Also, share your medical history and list of all the medicines you are taking with the doctor. Keep this medicine out of reach of children.
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